Vortxi Rituximab 500mg Injection

500mg Injection, Piece

4.5 (154)

₹8,500

Vortuxi 500mg Injection is a monoclonal antibody used to treat non-Hodgkin lymphoma, rheumatoid arthritis, chronic lymphocytic leukemia, and certain vasculitis conditions. It works by targeting immune B cells, reducing unwanted immune activity and killing cancer cells. Administered by a doctor, common side effects include headache, weakness, swelling, and increased infection risk due to reduced blood cell counts. Regular blood tests are needed, and it’s not recommended during pregnancy or breastfeeding.

Description

Introduction Of Vortuxi 500mg Injection:

Vortuxi 500mg Injection contains Rituximab, a monoclonal antibody used in the treatment of Non-Hodgkin’s Lymphoma (NHL), Chronic Lymphocytic Leukemia (CLL), Rheumatoid Arthritis, Granulomatosis with Polyangiitis (GPA) , Microscopic Polyangiitis (MPA), and Pemphigus Vulgaris.

Vortuxi 500mg Injection is administered only by a trained healthcare professional as a slow intravenous infusion after dilution. It must never be given as an intravenous push or bolus. Your doctor will decide the dose and schedule based on your condition and body surface area, and it may be combined with chemotherapy or other medicines. Medicines to reduce the risk of infusion reactions are usually given before each dose. It should never be self-administered.

Infusion-related reactions such as fever, chills, and itching are among the most common effects of this medicine, especially during the first infusion. Your doctor will monitor you closely during the infusion and may advise regular blood tests during treatment. Your doctor will also screen you for hepatitis B before starting treatment, as this medicine can reactivate it. Inform your doctor immediately if you notice difficulty breathing, swelling of the face or throat, severe rash, or signs of infection.

Uses Of Vortuxi 500mg Injection:

  • Rheumatoid arthritis
  • Blood cancer (Chronic lymphocytic leukemia)
  • Non-Hodgkin lymphoma (NHL)
  • Granulomatosis with polyangiitis
  • Microscopic polyangiitis

Benefits Of Vortuxi 500mg Injection:

1. Non-Hodgkin’s Lymphoma and Chronic Lymphocytic Leukemia

NHL and CLL are cancers that affect B-cells, a type of white blood cell. Vortuxi 500mg Injection targets a protein called CD20 on the surface of these cells, helping destroy the cancerous B-cells and control the growth and spread of the disease.

2. Rheumatoid Arthritis

In rheumatoid arthritis, overactive B-cells contribute to joint inflammation. Vortuxi 500mg Injection, used with methotrexate in patients who have not responded adequately to other treatments, helps reduce inflammation and pain and slows joint damage.

3. Autoimmune Conditions

In granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris, Vortuxi 500mg Injection helps control the overactive immune response by reducing the number of B-cells involved.

Side effects of Vortuxi 500mg Injection:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Common side effects of Rituximab:

  • Infusion-related reactions
  • Fever
  • Chills
  • Nausea
  • Headache
  • Fatigue
  • Skin rash and itching
  • Throat irritation
  • Low blood cell counts
  • Increased risk of infections

Machanism Of Action Of Vortuxi 500mg Injection:

Vortuxi 500mg InjectionRituximab, a chimeric monoclonal antibody that binds to the CD20 protein on the surface of B-cells. Once bound, it triggers the immune system and other mechanisms to destroy these cells, including cancerous B-cells and the overactive B-cells involved in autoimmune conditions. This helps control disease progression.

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Info Table
Strength 500mg
Packaging Size 50ml Vial
Brand Vortuxi 500mg
Composition RITUXIMAB – (500mg/50ml)
Manufacturer ZYDUS CADILA
Consume Type Parenteral
Treatment Non-Hodgkin’s Lymphoma (NHL) | Chronic Lymphocytic Leukemia (CLL) | Rheumatoid Arthritis | Granulomatosis with Polyangiitis (GPA) | Microscopic Polyangiitis (MPA)
Prescription/Non prescription Prescription
Form Injection (Concentrate for Solution for Infusion)
Country of Origin Made in India
Vendor Info
Benefits
Reviews

Description

Introduction Of Vortuxi 500mg Injection:

Vortuxi 500mg Injection contains Rituximab, a monoclonal antibody used in the treatment of Non-Hodgkin’s Lymphoma (NHL), Chronic Lymphocytic Leukemia (CLL), Rheumatoid Arthritis, Granulomatosis with Polyangiitis (GPA) , Microscopic Polyangiitis (MPA), and Pemphigus Vulgaris.

Vortuxi 500mg Injection is administered only by a trained healthcare professional as a slow intravenous infusion after dilution. It must never be given as an intravenous push or bolus. Your doctor will decide the dose and schedule based on your condition and body surface area, and it may be combined with chemotherapy or other medicines. Medicines to reduce the risk of infusion reactions are usually given before each dose. It should never be self-administered.

Infusion-related reactions such as fever, chills, and itching are among the most common effects of this medicine, especially during the first infusion. Your doctor will monitor you closely during the infusion and may advise regular blood tests during treatment. Your doctor will also screen you for hepatitis B before starting treatment, as this medicine can reactivate it. Inform your doctor immediately if you notice difficulty breathing, swelling of the face or throat, severe rash, or signs of infection.

Uses Of Vortuxi 500mg Injection:

  • Rheumatoid arthritis
  • Blood cancer (Chronic lymphocytic leukemia)
  • Non-Hodgkin lymphoma (NHL)
  • Granulomatosis with polyangiitis
  • Microscopic polyangiitis

Benefits Of Vortuxi 500mg Injection:

1. Non-Hodgkin’s Lymphoma and Chronic Lymphocytic Leukemia

NHL and CLL are cancers that affect B-cells, a type of white blood cell. Vortuxi 500mg Injection targets a protein called CD20 on the surface of these cells, helping destroy the cancerous B-cells and control the growth and spread of the disease.

2. Rheumatoid Arthritis

In rheumatoid arthritis, overactive B-cells contribute to joint inflammation. Vortuxi 500mg Injection, used with methotrexate in patients who have not responded adequately to other treatments, helps reduce inflammation and pain and slows joint damage.

3. Autoimmune Conditions

In granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris, Vortuxi 500mg Injection helps control the overactive immune response by reducing the number of B-cells involved.

Side effects of Vortuxi 500mg Injection:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Common side effects of Rituximab:

  • Infusion-related reactions
  • Fever
  • Chills
  • Nausea
  • Headache
  • Fatigue
  • Skin rash and itching
  • Throat irritation
  • Low blood cell counts
  • Increased risk of infections

Machanism Of Action Of Vortuxi 500mg Injection:

Vortuxi 500mg InjectionRituximab, a chimeric monoclonal antibody that binds to the CD20 protein on the surface of B-cells. Once bound, it triggers the immune system and other mechanisms to destroy these cells, including cancerous B-cells and the overactive B-cells involved in autoimmune conditions. This helps control disease progression.

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Frequently Asked Questions

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What is Vortuxi 500mg Injection used for?
Vortuxi Injection (Rituximab) is used to treat non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, and vasculitis conditions like granulomatosis with polyangiitis.
It is given as an infusion under a doctor’s supervision, with dosage and frequency determined based on your condition.
It works by targeting and destroying specific immune cells (B-cells), helping treat non-Hodgkin lymphoma and chronic lymphocytic leukemia, and reducing the overactive immune response in rheumatoid arthritis. See MedlinePlus Drug Information for more.
Regular blood tests are needed to monitor blood cell counts and check for hepatitis B before and during treatment.
No, it is not recommended during pregnancy or breastfeeding. Effective contraception is advised during treatment.
Vortuxi Injection is manufactured by Zydus Cadila, containing Rituximab 500mg, supplied as a 50ml vial, made in India.

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