Description
Sotorasib 120mg Tablets
Information Sotorasib is an oral targeted anticancer medication developed to inhibit KRAS G12C, amutation previously considered undruggable.
Mechanism of Action Sotorasib directly inhibits mutant KRAS signaling.- Binds irreversibly to KRAS G12C- Locks KRAS in an inactive GDP-bound state- Blocks downstream oncogenic signaling
Uses / Indications Used in genetically defined lung cancer.- KRAS G12C-mutated non-small cell lung cancer
Side Effects Most adverse effects are manageable.- Diarrhea- Fatigue- Elevated liver enzymes
Warnings & Precautions Monitoring is recommended.- Regular liver function testing- Assess gastrointestinal tolerance
Conclusion Sotorasib represents a major advancement in precision oncology by directly targeting KRAS-driven tumors.This information is intended for educational purposes only and should not replace clinicaljudgment. Treatment decisions must be made by qualified healthcare professionals.
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