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Sotorasib 120mg Tablets

Sotorasib 120mg Tablets

120mg Tablets, Bottle

4.5 (154)

₹24,500

Sotorasib 120mg Tablets is a targeted anticancer medication used to treat KRAS G12C-mutated non-small cell lung cancer. It works by irreversibly binding to the mutant KRAS G12C protein, locking it in an inactive state and blocking downstream cancer-driving signals. Common side effects include diarrhea, fatigue, and elevated liver enzymes, requiring regular liver function monitoring during treatment.

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Description

Sotorasib 120mg Tablets

Information Sotorasib is an oral targeted anticancer medication developed to inhibit KRAS G12C, amutation previously considered undruggable.

Mechanism of Action Sotorasib directly inhibits mutant KRAS signaling.- Binds irreversibly to KRAS G12C- Locks KRAS in an inactive GDP-bound state- Blocks downstream oncogenic signaling

Uses / Indications Used in genetically defined lung cancer.- KRAS G12C-mutated non-small cell lung cancer

Side Effects Most adverse effects are manageable.- Diarrhea- Fatigue- Elevated liver enzymes

Warnings & Precautions Monitoring is recommended.- Regular liver function testing- Assess gastrointestinal tolerance

Conclusion Sotorasib represents a major advancement in precision oncology by directly targeting KRAS-driven tumors.This information is intended for educational purposes only and should not replace clinicaljudgment. Treatment decisions must be made by qualified healthcare professionals.

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Category
Info Table
Strength 120 mg
Daily Dose Strength 120 mg
Brand Lucisot
Pack Size 56 tablets
Composition Sotorasib 120 mg
Form Tablet
Packaging Type Bottle
Vendor Info
Benefits
Reviews

Description

Sotorasib 120mg Tablets

Information Sotorasib is an oral targeted anticancer medication developed to inhibit KRAS G12C, amutation previously considered undruggable.

Mechanism of Action Sotorasib directly inhibits mutant KRAS signaling.- Binds irreversibly to KRAS G12C- Locks KRAS in an inactive GDP-bound state- Blocks downstream oncogenic signaling

Uses / Indications Used in genetically defined lung cancer.- KRAS G12C-mutated non-small cell lung cancer

Side Effects Most adverse effects are manageable.- Diarrhea- Fatigue- Elevated liver enzymes

Warnings & Precautions Monitoring is recommended.- Regular liver function testing- Assess gastrointestinal tolerance

Conclusion Sotorasib represents a major advancement in precision oncology by directly targeting KRAS-driven tumors.This information is intended for educational purposes only and should not replace clinicaljudgment. Treatment decisions must be made by qualified healthcare professionals.

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Frequently Asked Questions

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What is Sotorasib 120mg Tablet used for?
Sotorasib 120mg Tablet is used to treat certain types of non-small cell lung cancer (NSCLC) with a specific KRAS G12C mutation, and is also used for colorectal cancer with this mutation, typically in combination with another medicine, after other treatments haven’t worked.
It’s a KRAS inhibitor that irreversibly binds to the mutant KRAS G12C protein, locking it in an inactive state. This blocks the abnormal signal that tells cancer cells to multiply, helping stop or slow the spread of cancer.
It’s taken once daily, with or without food, at around the same time each day, exactly as your doctor directs. Consistency in timing helps maintain steady levels of the medicine in your body.
Reported side effects include diarrhea, fatigue, and elevated liver enzymes. Regular liver function testing is recommended during treatment to monitor for this effect, and your gastrointestinal tolerance may also be assessed.
For lung cancer, it’s often used alone. For colorectal cancer with a KRAS G12C mutation, it’s typically used in combination with another targeted therapy, following prior chemotherapy treatment.
No. As a specialized, genetically-targeted cancer medicine, Sotorasib requires a valid prescription and should only be used under close oncologist supervision with regular monitoring.

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