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Resmetirom 100mg Tablets

Resmetirom 100mg Tablets

100mg Tablets, Strip

4.5 (154)

₹5,000

Resmetirom 100mg Tablets is an oral therapy used to treat metabolic-associated steatohepatitis (MASH/NASH), an advanced form of fatty liver disease. It works by selectively activating hepatic THR-beta, reducing triglyceride and LDL cholesterol levels while improving liver histology over time. Common side effects include diarrhea and abdominal discomfort, and regular monitoring of liver function and thyroid parameters is recommended during treatment.

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Description

Resmetirom 100mg Tablets

Information Resmetirom 100mg represents an intensified oral therapy for metabolic-associated liverdisease.

Mechanism of Action Resmetirom exerts potent liver-directed metabolic effects.- Activates hepatic THR-beta selectively- Reduces triglyceride and LDL cholesterol levels- Improves liver histology over time

Uses / Indications Used in advanced metabolic liver disease.- Metabolic-associated steatohepatitis (MASH/NASH)

Side Effects Generally well tolerated.- Diarrhea- Abdominal discomfort- Transient biochemical changes

Warnings & Precautions Regular assessment recommended.- Monitor liver function- Evaluate thyroid parameters

Conclusion Resmetirom 100mg offers enhanced metabolic benefit in selected patients with fatty liverdisease.This information is intended for educational purposes only and should not replace clinicaljudgment. Treatment decisions must be made by qualified healthcare professionals.

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Category
Info Table
Strength 100 mg
Packaging Size 30 tablets
Form Tablet
Composition Resmetirom
Packaging Type Bottle
Shelf Life 18 Months
Prescription Non Prescription
Vendor Info
Benefits
Reviews

Description

Resmetirom 100mg Tablets

Information Resmetirom 100mg represents an intensified oral therapy for metabolic-associated liverdisease.

Mechanism of Action Resmetirom exerts potent liver-directed metabolic effects.- Activates hepatic THR-beta selectively- Reduces triglyceride and LDL cholesterol levels- Improves liver histology over time

Uses / Indications Used in advanced metabolic liver disease.- Metabolic-associated steatohepatitis (MASH/NASH)

Side Effects Generally well tolerated.- Diarrhea- Abdominal discomfort- Transient biochemical changes

Warnings & Precautions Regular assessment recommended.- Monitor liver function- Evaluate thyroid parameters

Conclusion Resmetirom 100mg offers enhanced metabolic benefit in selected patients with fatty liverdisease.This information is intended for educational purposes only and should not replace clinicaljudgment. Treatment decisions must be made by qualified healthcare professionals.

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Frequently Asked Questions

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What is Resmetirom 100mg Tablet used for?
Resmetirom treats metabolic dysfunction-associated steatohepatitis (MASH, formerly called NASH) in adults with moderate to advanced liver fibrosis (stages F2–F3), used alongside diet and exercise — not as a standalone treatment. It’s not approved for patients with cirrhosis (severe, advanced liver scarring), and the FDA granted approval under an accelerated pathway pending further confirmatory trial data.
It selectively activates a liver-specific thyroid hormone receptor (THR-beta), which reduces triglyceride and LDL cholesterol buildup and improves liver tissue health over time — effectively targeting the metabolic drivers of fatty liver disease directly in the liver rather than systemically.
No — it’s prescription-only. Given the liver monitoring requirements and contraindications involved, it should never be started or continued without physician oversight; any “non-prescription” listing for this drug is incorrect.
Regular liver function testing is needed throughout treatment, since dose-related liver enzyme elevations were observed within the first weeks of use in clinical trials (typically resolving by 8 weeks). It should be avoided in patients with moderate-to-severe liver impairment or decompensated cirrhosis. Watch for jaundice, dark urine, fatigue, nausea, or right-upper-abdominal pain and report these immediately.
Common effects include diarrhea, nausea, itching, vomiting, constipation, abdominal pain, and dizziness. It also carries a notable risk of gallbladder problems (gallstones, gallbladder inflammation) — report severe abdominal pain, especially radiating to the back, or persistent nausea/vomiting promptly.
Yes, but with real interaction risks: avoid combining with strong CYP2C8 inhibitors (e.g., gemfibrozil); dose reduction is needed with moderate inhibitors like clopidogrel. It also raises blood levels of several statins, so statin doses (rosuvastatin, simvastatin, pravastatin, atorvastatin) often need to be capped. Disclose all medications, especially cholesterol drugs, before starting.

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