Description
Introduction Of Religrast 300mcg Injection:
Religrast 300mcg Injection is a growth factor medicine used to treat neutropenia (a low count of infection-fighting white blood cells). Neutropenia may be caused by chemotherapy, bone marrow transplantation, severe chronic neutropenia, or HIV infection. It is also used before stem cell donation.
Religrast 300mcg Injection is given as a subcutaneous or intravenous injection using a single-dose pre-filled syringe. Your doctor or nurse will give it, or will teach you how to inject it correctly if self-injection is advised. Your doctor will decide the dose and how long you need it based on your medical condition and blood counts. It is usually not given within 24 hours before or after chemotherapy, as this can reduce how well it works. Store the syringe in a refrigerator (2°C to 8°C) and do not freeze it. Avoid crowded places and wash your hands often to lower the risk of infection.
Bone pain and headache are among the most common effects of this medicine. This happens as the bone marrow works to make new white blood cells. Your doctor may advise regular blood tests to monitor your blood counts. Inform your doctor immediately if you notice severe pain in the upper left side of your stomach or shoulder, difficulty breathing, or swelling of the face, as these need urgent medical attention.
Uses Of Religrast 300mcg Injection:
- Neutropenia caused by chemotherapy
- Neutropenia after bone marrow transplantation
- Severe chronic neutropenia
- Neutropenia in patients with HIV infection
- Mobilization of stem cells before stem cell donation
Benefits Of Religrast 300mcg Injection:
1. Neutropenia
Neutropenia is a condition in which the number of neutrophils (a type of white blood cell) in the blood is low. Neutrophils protect the body from infections, and a low count raises the risk of serious infections. Religrast 300mcg Injection stimulates the bone marrow to make more neutrophils, which helps the body fight infections and lowers the risk of fever and infection during cancer treatment.
2. Stem cell mobilization
Before stem cell donation, stem cells need to move from the bone marrow into the bloodstream so they can be collected. Religrast 300mcg Injection helps this process, making it easier to collect enough healthy stem cells.
Side effects of Religrast 300mcg Injection:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.
Common side effects of Religrast:
- Bone pain
- Weakness
- Headache
- Rash
- Nausea
- Vomiting
- Increased lactate dehydrogenase level in blood
- Increased uric acid level in blood
- Sore throat
- Hair loss
Mechanism Of Action Of Religrast 300mcg Injection:
Religrast Injection contains Filgrastim, a recombinant human granulocyte colony stimulating factor (G-CSF). It works by stimulating the bone marrow to produce more neutrophils, which are white blood cells that fight infections. This helps restore the body’s defense against infections.

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