Description
Introduction Of Jaknat 5mg Tablet:
Jaknat 5mg Tablet is a Janus kinase (JAK) inhibitor used in the treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. Each tablet contains Tofacitinib 5 mg.
Jaknat 5mg Tablet can be taken with or without food, but try to take it at the same time every day to get the most benefit. Your doctor will decide the dose and how often you need to take it. This will depend on the condition being treated and may change from time to time. Take it exactly as your doctor has advised. Taking it the wrong way or taking too much can cause serious side effects. It may take several weeks for you to feel the full benefits, so do not stop taking it unless your doctor tells you to.
Upper respiratory tract infections, headache, and diarrhea are the most common side effects of this medicine. It can lower your body’s ability to fight infections, so your doctor may advise regular blood tests to monitor blood counts, liver function, and cholesterol levels during treatment. Inform your doctor immediately if you experience fever, persistent cough, chills, or any sign of infection.
Uses Of Jaknat 5mg Tablet:
- Rheumatoid arthritis
- Psoriatic arthritis
- Ankylosing spondylitis
- Ulcerative colitis
Benefits Of Jaknat 5mg Tablet:
1. Rheumatoid arthritis
Rheumatoid arthritis is a long-term autoimmune condition in which the immune system attacks the joints, causing pain, swelling, and stiffness. This tablet helps reduce joint inflammation, relieve pain and stiffness, and slow joint damage, which may improve daily movement and quality of life.
2. Psoriatic arthritis
Psoriatic arthritis is an inflammatory joint condition that occurs in people who have psoriasis. This medicine helps control joint pain, swelling, and inflammation, and improves physical function in patients who have not responded well to other treatments.
3. Ankylosing spondylitis
Ankylosing spondylitis is an inflammatory condition that mainly affects the spine, causing back pain and stiffness. This tablet helps reduce inflammation in the spine and joints, easing pain and improving flexibility.
4. Ulcerative colitis
Ulcerative colitis is a chronic inflammatory bowel disease that causes swelling and sores in the lining of the large intestine. This medicine helps reduce inflammation in the gut, controls symptoms such as diarrhea, abdominal pain, and rectal bleeding, and helps maintain remission.
Side Effects Of Jaknat 5mg Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you are worried about them.
Common side effects of Tofacitinib:
- Headache
- Diarrhea
- Nausea
- Common cold (nasopharyngitis)
- Upper respiratory tract infection
- Skin rash
- Increased cholesterol levels
- Increased liver enzymes
Serious side effects such as severe infections, tuberculosis, shingles (herpes zoster), blood clots, heart-related problems, and certain cancers are possible. Seek medical help immediately if you notice chest pain, shortness of breath, swelling in the legs, or signs of a serious infection.
Mechanism Of Action Of Jaknat 5mg Tablet:
Jaknat 5mg Tablet is an immunomodulator (JAK inhibitor). It works by blocking Janus kinase enzymes (mainly JAK1 and JAK3) inside immune cells. These enzymes pass on signals from inflammatory messengers called cytokines, which drive inflammation and immune activity. By interrupting these signals, the medicine reduces the overactive immune response and the inflammation that damages joints and the intestinal lining. This is how it works against autoimmune conditions.
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