Description
Introduction Of Azacitidine 300mg Tablet:
Azacitidine 300mg Tablet is an oral anti-cancer medicine used for continued treatment of acute myeloid leukemia (AML) in adults. It is given to patients who improved after intensive chemotherapy but are not able to complete intensive curative therapy. It is also used in myelodysplastic syndrome and chronic myelomonocytic leukemia .
Azacitidine 300mg Tablet can be taken with or without food, but try to take it at the same time every day to get the most benefit. Your doctor will decide the dose and treatment schedule based on your medical condition and blood counts, and it is usually taken in cycles. Swallow the tablet whole with water. Do not chew, crush, or break it. Your doctor may prescribe an anti-nausea medicine to take before each dose. This medicine can harm an unborn baby and may affect fertility, so both men and women should use effective contraception during treatment. Avoid alcohol and drink plenty of water. Do not stop taking it unless your doctor tells you to.
Nausea, vomiting, diarrhea, and constipation are among the most common effects of this medicine. This medicine may lower your blood cell counts, making infections and bruising more likely. Your doctor will advise regular blood tests. Inform your doctor immediately if you notice fever, chills, a sore throat that does not go away, unusual bruising or bleeding, severe diarrhea, or yellowing of the skin or eyes.
Uses Of Azacitidine 300mg Tablet:
- Acute myeloid leukemia (AML)
- Myelodysplastic syndrome (MDS)
- Chronic myelomonocytic leukemia (CMML)
Benefits Of Azacitidine 300mg Tablet:
1. Acute myeloid leukemia
Acute myeloid leukemia is a cancer that forms in the blood-forming cells of the bone marrow. Azadine-O 300mg Tablet is used to keep the disease under control in adults who have responded to earlier chemotherapy. It interferes with the growth of cancer cells, which are eventually destroyed by the body, helping maintain remission.
2. Myelodysplastic syndrome and chronic myelomonocytic leukemia
Myelodysplastic syndrome is a group of conditions in which the bone marrow makes abnormal blood cells and fails to make enough healthy ones. Azadine-O 300mg Tablet kills abnormal cells in the bone marrow and helps it produce and mature healthy new blood cells.
Side effects of Azacitidine 300mg Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.
Common side effects of Azadine-O:
- Nausea
- Vomiting
- Constipation
- Fatigue
- Abdominal pain
- Decreased potassium level in blood
- Bruising
- Dizziness
- Decreased appetite
- Joint pain
Mechanism Of Action Of Azacitidine 300mg Tablet:
Azacitidine 300mg Tablet contains Azacitidine, a nucleoside metabolic inhibitor (demethylating agent). It gets built into the genetic material (DNA and RNA) of cells and interferes with the production of new DNA and RNA. This kills abnormal cancer cells and helps restore the normal maturation and growth of young blood cells in the bone marrow.

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